Lithium iodide → HCID 20324151, compound

HRID 616299Notes

Reaction equation

COC([C:5]1([CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH:9]([CH2:10][S:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:8][CH2:7][C:6]1=[O:18])=O.[I-].[Li+]>>[CH2:23]([O:22][C:20]([CH2:19][CH:5]1[CH:9]([CH2:10][S:11][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:8][CH2:7][C:6]1=[O:18])=[O:21])[CH3:24]

Participants

Reactant 2

HCID 66321Lithium iodide

HCID 54118314HCID 54118314, compound

Product 1

HCID 20324151HCID 20324151, compoundYield 78.7%

Procedure

In accordance with the process of Example 25, 1-ethoxycarbonylmethyl-2-oxo-5-phenylthiomethyl-cyclopentanecarboxylic acid methyl ester (640 mg; 1.83 m mol) and lithium iodide (250 mg; 1.85 m mol) were used to obtain 420 mg of 2-ethoxycarbonylmethyl-3-phenylthiomethyl-cyclopentanone as an oil.

Sources & evidence

ORD record: ord-7626968826e34b498d1dd42f39e0bca0
Source dataset: uspto-grants-1978_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04073799

Reaction notes

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