Acetaldehyde → HCID 54363972, compound

HRID 616313Notes

Reaction equation

HRID 616313 reaction equation
C(O[CH:4](OCC)[CH2:5][CH2:6][CH:7]([NH2:12])[CH2:8][CH2:9][CH2:10][CH3:11])C.Cl.[CH2:17]([O:19][C:20](=[O:30])[CH2:21][C:22](=[O:29])[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])[CH3:18].[CH:31](=O)[CH3:32].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[CH3:31][CH:32]1[CH:23]([C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:22](=[O:29])[CH:21]([C:20]([O:19][CH2:17][CH3:18])=[O:30])[CH:4]2[N:12]1[CH:7]([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5]2

Participants

7

Reactant 5

HCID 177AcetaldehydeHCID 313Hydrochloric AcidHCID 10340Sodium CarbonateHCID 66045Diethyl acetonedicarboxylateHCID 20369575HCID 20369575, compound

Product 1

HCID 54363972HCID 54363972, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 434 g (2 (Mol) 4-amino-octanal diethyl-acetal in 2 liters of ethanol (water free) was brought to pH4 with 0.5 N hydrochloric acid. To this solution 404 g (2 Mol) diethyl-3-oxo- glutarate and 88 g (2 Mol) acetaldehyde were added. The reaction mixture was stirred during three days at room temperature and was then brought to pH7 to 8 by addition of sodium carbonate powder.

Sources & evidence

ORD record
ord-40459d80e8d544c599d723790c55694f
Source dataset
uspto-grants-1978_02
Patent number
US04073882

Reaction notes

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