HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine, 1-(2-chloroethyl)-, hydrochloride → Piperidine, 1-(2-(2-butoxyphenoxy)ethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine, 1-(2-chloroethyl)-, hydrochloride | HCID 74826 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | o-Butoxyphenol | HCID 12447746 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Piperidine, 1-(2-(2-butoxyphenoxy)ethyl)- | HCID 3042676 | — |
Reaction Steps
The compound was prepared as described in Example 1, using sodium (2.3 g, 100 mmole), o-butoxyphenol (8.30 g, 50 mmole) and piperidinoethylchloride hydrochloride (9.2 g, 50 mmole) in 150 ml of ethanol. Yield 4.4 g (32%) of product boiling at 121° C under a pressure of 0.02 mm Hg; nD25 1.5135.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04073917 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-47436bb577754538ad72349319371715 |
| Source note | uspto-grants-1978_02 |