Methyl iodide → HCID 20368075, compound

HRID 616570Notes

Reaction equation

HRID 616570 reaction equation
ClC1N=CC2C(=O)N3N=CC=C3NC=2C=1.CI.[Cl:18][C:19]1[N:28]=[CH:27][C:26]2[C:25](=[O:29])[N:24]3[N:30]=[C:31](C)[CH:32]=[C:23]3[N:22]([CH3:34])[C:21]=2[CH:20]=1>>[Cl:18][C:19]1[N:28]=[CH:27][C:26]2[C:25](=[O:29])[N:24]3[N:30]=[CH:31][CH:32]=[C:23]3[N:22]([CH3:34])[C:21]=2[CH:20]=1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 20368067HCID 20368067, compoundHCID 178515173HCID 178515173, compound

Product 1

HCID 20368075HCID 20368075, compoundYield 76%

Procedure

By treating 6-chloropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one of Example 1 with methyl iodide according to the procedure of Example 5 for the preparation of 6-chloro-2,4-dimethylpyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one, 6-chloro-4-methylpyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one is obtained, yield: 76%; m.p. >300°.

Sources & evidence

ORD record
ord-86c7912cce7a4b67b8f215a68b9115b0
Source dataset
uspto-grants-1978_02
Patent number
US04075210

Reaction notes

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