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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 616592Generated: October 29, 2026

Sodium hydride → Dipropylaminopropyl chloride

https://huagongshe.com/reaction/616592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant8-chloro-6-(o-chlorophenyl)-1H-s-triazolo[4,3-a][1,5]benzodiazepin-1,5-(2H,6H)-dioneHCID 20367934—
ProductDipropylaminopropyl chlorideHCID 12333917—
Product8-chloro-2-[(dipropylamino)propyl]-6-(o-chlorophenyl)-1H-s-triazolo[4,3-a][1,5]benzodiazepin-1,5-(2H,6H)-dioneHCID 20368021—

Reaction Steps

In the manner given in Example 21, 8-chloro-6-(o-chlorophenyl)-1H-s-triazolo[4,3-a][1,5]benzodiazepin-1,5-(2H,6H)-dione can be reacted with sodium hydride and then with dipropylamino propyl chloride to give 8-chloro-2-[(dipropylamino)propyl]-6-(o-chlorophenyl)-1H-s-triazolo[4,3-a][1,5]benzodiazepin-1,5-(2H,6H)-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04075202
Source datasetuspto-grants-1978_02
ORD IDord-b2f332cf91ce4c4585cc0985da87b799
Source noteuspto-grants-1978_02