HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20368141, compound → HCID 20368148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20368141 | HCID 20368141 | — |
| Solvent | N,N,N',N'-Tetramethylmethanediamine | HCID 5829 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Acetyl chloride | HCID 6367 | — |
| Product | HCID 20368148 | HCID 20368148 | — |
Reaction Steps
In the manner given in Example 1, a solution of 7-chloro-1-methyl-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in dimethylformamide, N,N,N',N'-tetramethyldiaminomethane and acetyl chloride (in 0.25 molar excess compared to the N,N,N',N'-tetramethyldiaminomethane) are reacted together to give 7-chloro-1-[2-(dimethylamino)ethyl]-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04075221 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-b7798d3646974557b4fb4311a62d080d |
| Source note | uspto-grants-1978_02 |