HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19010444, compound → HCID 20368140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19010444 | HCID 19010444 | — |
| Solvent | N,N,N',N'-Tetramethylmethanediamine | HCID 5829 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Acetyl chloride | HCID 6367 | — |
| Product | HCID 20368140 | HCID 20368140 | — |
Reaction Steps
In the manner given in Example 1, a solution of 8-trifluoromethyl-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine in dimethylformamide, N,N,N',N'-tetramethyldiaminomethane and acetyl chloride (in 0.1 molar excess compared to the N,N,N', N'-tetramethyldiaminomethane) are reacted together to give 8-trifluoromethyl-1-[2-(dimethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04075221 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-6c42e22ffec64243b62350e69926640d |
| Source note | uspto-grants-1978_02 |