HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 20368144, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 20368138 | HCID 20368138 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20368144 | HCID 20368144 | — |
Reaction Steps
In the manner given in Example 1, a solution of 8-trifluoromethyl-1-methyl-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in dimethylformamide, N,N,N',N'-tetrapropyldiaminomethane and acetyl chloride (in 0.1 molar excess compared to the N,N,N',N'-tetrapropyldiaminomethane) are reacted together to give 8-trifluoromethyl-1-[2-(dipropylamino)ethyl]-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4-]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04075221 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-718ee3becdf949c89550cacef1cd00f4 |
| Source note | uspto-grants-1978_02 |