HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
9-trifluoromethyl-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine → 9-trifluoromethyl-1-[2-(diethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 9-trifluoromethyl-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 20368147 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Lösungsmittel | Acetyl bromide | HCID 10482 | — |
| Lösungsmittel | Tetraethylmethylenediamine | HCID 66020 | — |
| Produkt | 9-trifluoromethyl-1-[2-(diethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 20368142 | — |
Reaktionsschritte
In the manner given in Example 1, a solution of 9-trifluoromethyl-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine in dimethylformamide, N,N,N',N',-tetraethyldiaminomethane and acetyl bromide (in 0.2 molar excess compared to the N,N,N',N'-tetraethyldiaminomethane) are reacted together to give 9-trifluoromethyl-1-[2-(diethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04075221 |
| Quelldatensatz | uspto-grants-1978_02 |
| ORD ID | ord-dbf5a7df7b1a4e2280b28838e2842aa5 |
| Quellennotiz | uspto-grants-1978_02 |