s-Triazolo(5,1-a)isoquinoline, 5,6-dihydro-2-phenyl- → s-Triazolo(5,1-a)isoquinoline, 2-phenyl-

HRID 616696Notes

Reaction equation

HRID 616696 reaction equation
[C:1]1([C:7]2[N:19]=[C:10]3[C:11]4[C:16]([CH2:17][CH2:18][N:9]3[N:8]=2)=[CH:15][CH:14]=[CH:13][CH:12]=4)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(OCC)(=O)C>[C:1]1([C:7]2[N:19]=[C:10]3[C:11]4[C:16]([CH:17]=[CH:18][N:9]3[N:8]=2)=[CH:15][CH:14]=[CH:13][CH:12]=4)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 1

HCID 134397s-Triazolo(5,1-a)isoquinoline, 5,6-dihydro-2-phenyl-

Product 1

HCID 169678s-Triazolo(5,1-a)isoquinoline, 2-phenyl-Yield 56%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Following substantially the same procedures of Example 58, and starting from 2-phenyl-5,6-dihydro-s-triazolo[5,1-a]isoquinoline, the title compound is prepared. Yield 56%, m.p. 157°-8° C (from ethyl acetate).

Sources & evidence

ORD record
ord-e5b40dc425814361a186da3a64f6d9fb
Source dataset
uspto-grants-1978_02
Patent number
US04075341

Reaction notes

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