HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-Undecylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 1-Bromoundecane | HCID 12744 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Undecylpiperazine | HCID 12930911 | — |
Reaction Steps
Excess piperazine (5 eq) and 1-bromoundecane (1.0 eq) are dissolved in dichloromethane and allowed to react overnight. The mixture is extracted with aqueous sodium bicarbonate and the organic layer dried with sodium sulfate. The mixture is filtered, the solvent removed in vacuo and the residue purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05948753 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-1699726efc0f411d92dacde0e031d07a |
| Source note | uspto-grants-1999_09 |