Diethanolamine → HCID 21851225, compound

HRID 617172Notes

Reaction equation

Cl[C:2]1[N:11]=[C:10]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][CH2:19][NH:20][C:21](=[O:32])[C:22]3[CH:27]=[C:26]([CH3:28])[CH:25]=[CH:24][C:23]=3[N+:29]([O-:31])=[O:30])[CH2:14][CH2:13]2)[C:9]2[C:4](=[CH:5][C:6]([O:35][CH3:36])=[C:7]([O:33][CH3:34])[CH:8]=2)[N:3]=1.[NH:37]([CH2:41][CH2:42][OH:43])[CH2:38][CH2:39][OH:40]>>[OH:40][CH2:39][CH2:38][N:37]([CH2:41][CH2:42][OH:43])[C:2]1[N:11]=[C:10]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][CH2:19][NH:20][C:21](=[O:32])[C:22]3[CH:27]=[C:26]([CH3:28])[CH:25]=[CH:24][C:23]=3[N+:29]([O-:31])=[O:30])[CH2:14][CH2:13]2)[C:9]2[C:4](=[CH:5][C:6]([O:35][CH3:36])=[C:7]([O:33][CH3:34])[CH:8]=2)[N:3]=1

Participants

Reactant 2

HCID 8113Diethanolamine

HCID 21851294HCID 21851294, compound

Product 1

HCID 21851225HCID 21851225, compoundYield 71%

Procedure

The same procedure as in Reference Example 11 was repeated, except that 4.0 g (7.80 mmol) of Compound m was used, and diethanolamine was used in place of morpholine, to give 3.24 g (yield: 71%) of Compound o as white crystals.

Sources & evidence

ORD record: ord-2923fd2f425649748697fe6b931a9a0e
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05948784

Reaction notes

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