反应详情

Following the procedure of Example 16a, replacing the 5-chloro-3-(N-t-butoxycarbonyl-2-S)-pyrrolidinylmethoxy)pyridine thereof with 5-chloro-3-(N-t-butoxycarbonyl-2-(R)-pyrrolidinylmethoxy)pyridine (prepared from the (R)-isomer of the starting material following the procedure of Example 15a), the tide compound was prepared. TLC Rf =0.23 (10% MeOH/CHCl3). MS and 1H NMR (CDCl3, 300 MHz) are similar to 16a.

1. customwas prepared