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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 617601Generated: October 30, 2026

Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

https://huagongshe.com/reaction/617601

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl ethylmalonateHCID 8610—
ReactantHCID 53718772HCID 53718772—
Product2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanolHCID 22618796—

Reaction Steps

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05948820
Source datasetuspto-grants-1999_09
ORD IDord-46539a9f00db4d518e5ff82697b519a2
Source noteuspto-grants-1999_09