HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Fluorobenzimidic acid ethyl ester hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Fluorobenzonitrile | HCID 14517 | — |
| Product | 4-Fluorobenzimidic acid ethyl ester hydrochloride | HCID 12282159 | — |
Reaction Steps
Ethyl 4-fluorobenzimidate hydrochloride was synthesized in the same manner as in Reference Example 2. That is, 4-fluorobenzonitrile (50.8 g, 0.407 mol) was treated with hydrogen chloride in ethanol (500 mL) to give 82.1 g (99%) of the target compound as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05948785 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-96886884dc384d9bb54569d995d1b8b5 |
| Source note | uspto-grants-1999_09 |