HCID 21849682, compound → HCID 21849672, compound

HRID 617746Notes

Reaction equation

HRID 617746 reaction equation
[CH3:1][N:2]1[C:19](=[O:20])[CH2:18][CH2:17][C:5]2([C:9]3[CH:10]=[C:11]([N+:14]([O-])=O)[CH:12]=[CH:13][C:8]=3[O:7][CH2:6]2)[CH2:4][CH2:3]1>C(O)(=O)C>[NH2:14][C:11]1[CH:12]=[CH:13][C:8]2[O:7][CH2:6][C:5]3([CH2:17][CH2:18][C:19](=[O:20])[N:2]([CH3:1])[CH2:3][CH2:4]3)[C:9]=2[CH:10]=1

Participants

3

Reactant 1

HCID 21849682HCID 21849682, compound

Product 1

HCID 21849672HCID 21849672, compoundYield 31%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

This material was prepared from 1,2,3,5,6,7-hexahydro-1-methyl-5'-nitro-7-oxospiro[4H-azepine-4,3'(2H)-benzofuran] (D27, 0.68 g, 2.5 mmol) following the procedure of DESCRIPTION 6, but using acetic acid as solvent. This gave the title compound (0.19 g, 31%) as a white solid.

Sources & evidence

ORD record
ord-8a4f9b942352446eb5979cdcbb76fe89
Source dataset
uspto-grants-1999_09
Patent number
US05952325

Reaction notes

Loading…