HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fingolimod → Fingolimod Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fingolimod | HCID 107970 | — |
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Fingolimod Hydrochloride | HCID 107969 | — |
Reaction Steps
2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol (7 g) was dissolved in ethanol (50 ml) and a 1 N hydrochloric acid/ether solution (50 ml) was added thereto. The solvent was distilled away and the resultant crystals were recrystallized from ethanol to give 4.2 g of the subject compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952316 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-af1d16095e434800ae3b3fe9d4eec219 |
| Source note | uspto-grants-1999_09 |