HCID 53886611, compound → HCID 53671633, compound

Participants

Reaction Steps

3.5 g of 1-benzylethylphosphonomethyl-1-cyclopentanecarboxylic acid (preparation see Example 3E)) were dissolved in 150 ml of ethanol and treated with 1.0 g of 5% strength Pd catalyst on active carbon. The mixture was then hydrogenated at a hydrogen pressure of 2.1 bar for 4 hours. The catalyst was filtered out twice, the filtrate was evaporated in vacuo, and the residue was dried in a high vacuum. 2.60 g of oily 1-ethylphosphonomethyl-1-cyclopentanecarboxylic acid were obtained, which was reacted without further purification.

Provenance & Evidence