HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6-(2,4,6-Trimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,4-Diaminopyrimidine-5-carbaldehyde | HCID 309176 | — |
| Reactant | 2,4,6-Trimethylphenylacetonitrile | HCID 520698 | — |
| Solvent | Methane | HCID 297 | — |
| Product | 6-(2,4,6-Trimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine | HCID 21850022 | — |
Reaction Steps
The title compound was prepared according to Example 1, starting from 0.915 g of 2,4,6-trimethyl-benzyl cyanide and 0.76 g of 2,4-diamino-5-pyrimidine-carboxaldehyde; mp 276-282° C.; CIMS (1% ammonia in methane): m/z (relative intensity) 279 (MH+, 54), 280 (MH+ +1, 100)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952342 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-ef24aac75e154f329edbecc3e5235834 |
| Source note | uspto-grants-1999_09 |