HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Mercaptoethanol → 2-(2-Hydroxyethylthio)-3',4',5'-trimethoxyacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Mercaptoethanol | HCID 1567 | — |
| Reactant | 2-Bromo-1-(3,4,5-trimethoxyphenyl)ethanone | HCID 3685732 | — |
| Product | 2-(2-Hydroxyethylthio)-3',4',5'-trimethoxyacetophenone | HCID 21850175 | 76.9% |
Reaction Steps
Substantially the same procedure as in Reference Example 13 was repeated using 2-mercaptoethanol (0.82 g) and 2-bromo-3',4',5'-trimethoxyacetophenone (Compound XIa, 2.60 g) obtained in Reference Example 1 to give 2-(2-hydroxyethylthio)-3',4',5'-trimethoxyacetophenone (Compound IX-12, 1.98 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952355 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-7795b3aedea84dec850e9e70695b0319 |
| Source note | uspto-grants-1999_09 |