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HRID618162

反应详情

EQUATION

反应方程式

HRID 618162 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)NCC(=O)O
HCID78288

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-

C7H13NO4

结构：C[C@@H](N)CC(=O)OCc1ccccc1
HCID10867189

(R)-BENZYL 3-AMINOBUTYRATE

C11H15NO2

PRODUCTS

生成物

1
结构：C[C@H](CC(=O)OCc1ccccc1)NC(=O)CNC(=O)OC(C)(C)C
HCID86751222

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

N-(t-Butoxycarbonyl)glycine 14-3 (Aldrich) was coupled with 3(R)-methyl-β-alanine benzyl ester 0.5 H2SO4 11-7 (Celgene) according to the procedure described for the preparation of 14-5. The title product 15-1 was then obtained by chromatography (silica, hexane/EtOAc 2:3).

WORKUP

后处理

  1. customdescribed for the preparation of 14-5