Hydrochloric Acid → HCID 69351950, compound

HRID 618205Notes

Reaction equation

HRID 618205 reaction equation
[C:1]([CH2:3][O:4][C:5]1[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=1)#[N:2].[ClH:16].[CH2:17]([OH:19])[CH3:18]>C(Cl)(Cl)Cl>[ClH:16].[CH2:17]([O:19][C:1](=[NH:2])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:6]=1)[CH3:18]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 18789601N-(3-cyanomethoxyphenyl)methanesulfonamide

Product 1

HCID 69351950HCID 69351950, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

N-(3-Cyanomethoxyphenyl)-methanesulfonamide (1.0 g) was dissolved in a mixture of 20 ml of chloroform and 0.25 ml of absolute ethanol (EtOH). The reaction mixture was cooled in an ice bath and saturated with hydrogen chloride gas. The mixture was slowly allowed to come to room temperature and stirred for 16 hours. The solvent was evaporated leaving 1.1 g of 2-(3-methanesulfonylaminophenoxy)-acetimidic acid ethyl ester hydrochloride. ##STR57##

Workup

  1. customto come to room temperature
  2. customThe solvent was evaporated

Sources & evidence

ORD record
ord-83c2af5777f349a495a87990ca602cfc
Source dataset
uspto-grants-1999_09
Patent number
US05952362

Reaction notes

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