Trifluoroacetic acid → HCID 178454634, compound

HRID 618356Notes

Reaction equation

[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[NH2:8][N:9]=[CH:10][NH:11][C:12]1[CH:13]=[C:14]([C:18]([NH:20][C:21]2[CH:26]=[CH:25][C:24]([CH:27]([CH3:36])[CH2:28][C:29]([O:31]C(C)(C)C)=[O:30])=[CH:23][CH:22]=2)=[O:19])[CH:15]=[CH:16][CH:17]=1.C(O)(C(F)(F)F)=O>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[NH2:8][N:9]=[CH:10][NH:11][C:12]1[CH:13]=[C:14]([C:18]([NH:20][C:21]2[CH:26]=[CH:25][C:24]([CH:27]([CH3:36])[CH2:28][C:29]([OH:31])=[O:30])=[CH:23][CH:22]=2)=[O:19])[CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 178454690HCID 178454690, compound

Product 1

HCID 178454634HCID 178454634, compound

Procedure

The compound of Example 30 was hydrolyzed with TFA under conditions similar to those described in Example 33.

Sources & evidence

ORD record: ord-c407e830d54f4794b85b4d9a12dd39f0
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05952381

Reaction notes

Loading…