反应详情

A solution of 1-t-butoxycarbonyl-4-(3-propyl-2-oxo-1-benzimidazolinyl)piperidine (540 mg, 1.5 mmol) in chloroform (7 mL) containing trifluoroacetic acid (1 mL) was allowed to stir at ambient temperature for 15-25 hours. The solvent was removed on a rotary evaporator, the residue dissolved in chloroform and washed with aq. Na2CO3. The dried (Na2SO4) chloroform extract was evaporated to give 4-(3-propyl-2-oxo-1-benzimidazolinyl)piperidine as an oil which was used as is.

1. customThe solvent was removed on a rotary evaporator
2. dissolutionthe residue dissolved in chloroform
3. washwashed with aq. Na2CO3
4. dry with materialThe dried (Na2SO4) chloroform
5. extractionextract
6. customwas evaporated