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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 618375Generated: October 29, 2026

1-(Piperidin-4-yl)-3-propyl-1,3-dihydro-2H-benzimidazol-2-one → 1,1-Dioxido-2-(4-(4-(3-n-propyl-2-oxo-1-benzimidazolinyl)piperidin-1-yl)pentyl)-5-chloro-1,2-benzisothiazol-3(2H)-one

https://huagongshe.com/reaction/618375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Piperidin-4-yl)-3-propyl-1,3-dihydro-2H-benzimidazol-2-oneHCID 15895135—
Reactant1,1-dioxido-2-(4-oxo-pentyl)-5-chloro-1,2-benzisothiazol-3(2H)-oneHCID 18695979—
Product1,1-Dioxido-2-(4-(4-(3-n-propyl-2-oxo-1-benzimidazolinyl)piperidin-1-yl)pentyl)-5-chloro-1,2-benzisothiazol-3(2H)-oneHCID 18695967—

Reaction Steps

Starting with 4-(3-n-propyl-2-oxo-1-benzimidazolinyl)piperidine and 1,1-dioxido-2-(4-oxo-pentyl)-5-chloro-1,2-benzisothiazol-3(2H)-one and following the procedure of Example 13, the title compound is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05952351
Source datasetuspto-grants-1999_09
ORD IDord-14472566878a49b38528865ec60c8a7c
Source noteuspto-grants-1999_09