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HRID618467

反应详情

EQUATION

反应方程式

HRID 618467 的结构方程式

REACTANTS

反应物

2
结构：N[C@@H](CCC(=O)O)C(=O)O
HCID33032

L-Glutamic acid

C5H9NO4

结构：CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1
HCID126941

Methotrexate

C20H22N8O5

PRODUCTS

生成物

1
结构：CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccccc1C(=O)O
HCID70031183

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by carboxypeptidase G cleavage of glutamic acid from methotrexate as described in the literature (J. Med. Chem. 24, 1450-1455 (1981)). The yield of I obtained was virtually quantitative.

WORKUP

后处理

  1. customThe yield of I obtained