Dimethoxymethane → HCID 70231390, compound

HRID 618507Notes

Reaction equation

HRID 618507 reaction equation
[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([C:21]5[CH:30]=[CH:29][C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:23][CH:22]=5)=[CH:18]4)=[CH:13][C:12]=3[CH2:31][CH2:32][CH2:33][OH:34])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:35][O:36][CH2:37]OC>C[Si](I)(C)C.O>[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([C:21]5[CH:22]=[CH:23][C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:29][CH:30]=5)=[CH:18]4)=[CH:13][C:12]=3[CH2:31][CH2:32][CH2:33][O:34][CH2:35][O:36][CH3:37])[CH2:8][CH:7]3[CH2:9][CH:3]([CH2:4][CH:5]([CH2:6]3)[CH2:10]1)[CH2:2]2

Participants

5

Reactant 2

HCID 8020DimethoxymethaneHCID 70231396HCID 70231396, compound

Product 1

HCID 70231390HCID 70231390, compound

Reagents, catalysts & solvents 2

HCID 85247Trimethylsilyl iodideCatalystHCID 962WaterSolvent

Procedure

541 mg (1.2 mmol) of methyl 4-[7-(1-adamantyl)-6-hydroxypropyl-2-naphthyl]benzoate and 5 ml of dimethoxymethane were introduced into a round-bottomed flask and 5 drops of trimethylsilyl iodide were added. The reaction mixture was stirred at room temperature for 24 hours, was poured into water and extracted with ethyl ether and the organic phase was separated by settling, dried over magnesium sulfate and evaporated.

Workup

  1. extractionextracted with ethyl ether
  2. customthe organic phase was separated
  3. dry with materialdried over magnesium sulfate
  4. customevaporated

Sources & evidence

ORD record
ord-7a298a684383489789289a1db91bf9f7
Source dataset
uspto-grants-1999_09
Patent number
US05952382

Reaction notes

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