Diethyl Ether → HCID 21848303, compound

Participants

Reaction Steps

0.55 g (2.8 mmol) of 5,6-difluorobenzofuran-2-carboxamidine was dissolved in 10 ml of methanol-HCI (2.6N) and treated at room temperature while stirring with 100 ml of diethyl ether. The mixture was stirred for a further 3 hours and the white crystals were subsequently filtered off. There was obtained 0.61 g (87%) of 5,6-difluorobenzofuran-2-carboxamidine hydrochloride with m.p. >270°.

Provenance & Evidence