HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 15859751, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 21848681 | HCID 21848681 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15859751 | HCID 15859751 | — |
Reaction Steps
A solution of 0.4 g (1 mmol) of methyl 5-[ethylsulfonyl-(2,2,6-trimethyl-chroman-4-yl)amino]pentanoate and 1.5 ml of liquid ammonia in 10 ml of methanol is allowed to stand at RT for 9 days. After concentrating in vacuo, the residue is treated with water and extracted with EA. 0.37 g of 5-[ethylsulfonyl-(2,2,6-trimethylchroman-4-yl)amino]pentanamide is obtained; m.p. 127-129° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05955607 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-3838ea6664b64db2a48a532c1f5f9357 |
| Source note | uspto-grants-1999_09 |