HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 6-Fluoro-2,2-dimethyl-4-chromanone oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 6-fluoro-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one | HCID 11063293 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 6-Fluoro-2,2-dimethyl-4-chromanone oxime | HCID 85757782 | — |
Reaction Steps
By heating 10 mmol of 6-fluoro-2,2-dimethyl-4-chromanone with 12 mmol of hydroxylamine hydrochloride in 5 ml of methanol and 5 ml of pyridine for 2 hours to 80° C., after distilling off the solvent and precipitating with water, 6-fluoro-2,2-dimethyl-4-chromanone oxime is obtained; m.p. 108-110° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05955607 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-9b8a42da1bf9488eaee2162c911c710f |
| Source note | uspto-grants-1999_09 |