反应详情

By heating 10 mmol of 6-fluoro-2,2-dimethyl-4-chromanone with 12 mmol of hydroxylamine hydrochloride in 5 ml of methanol and 5 ml of pyridine for 2 hours to 80° C., after distilling off the solvent and precipitating with water, 6-fluoro-2,2-dimethyl-4-chromanone oxime is obtained; m.p. 108-110° C.

1. distillationafter distilling off the solvent
2. customprecipitating with water