HCID 86754517, compound → HCID 21848664, compound

Participants

Reaction Steps

1.4 g of methyl [(6-benzyloxy-2,2-dimethylchroman-4-yl)methanesulfonylamino]acetate are stirred at RT for 4 h in 50 ml of methanol and 15 ml of 2N NaOH. After removing the methanol, the residue is washed with EA and acidified with HCl. It is extracted with EA and the solvent is removed in vacuo after drying. 500 mg of the acid having a melting point of 167-169° C. are obtained.

Provenance & Evidence