Pyridine → HCID 67556213, compound

HRID 619100Notes

Reaction equation

HRID 619100 reaction equation
C([O:13]C1C=CC(N(OC(C)C(O)C)OC(C)C(O)C)=C(CCC)C=1)CCCCCCCCCCC.N1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1.CN([C:45]1[CH:50]=[CH:49][CH:48]=[CH:47]N=1)C.[C:51]1(P(Cl)(Cl)=O)[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=1.[CH2:61]([O:65][CH2:66][CH:67]1[CH2:74][N:73]([C:75]2[CH:80]=[CH:79][C:78]([O:81][CH2:82][CH2:83]CCCCCCCCCC)=[CH:77][CH:76]=2)[CH2:72][CH:71]([CH2:94][O:95][CH2:96][CH2:97][CH2:98][CH3:99])[O:70][P:69](=[O:106])(C2C=CC=CC=2)[O:68]1)[CH2:62][CH2:63][CH3:64]>ClCCl>[CH2:61]([O:65][CH2:66][CH:67]1[CH2:74][N:73]([C:75]2[CH:80]=[CH:79][C:78]([O:81][CH2:82][CH2:83][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:47][CH2:48][CH2:49][CH2:50][CH3:45])=[CH:77][CH:76]=2)[CH2:72][CH:71]([CH2:94][O:95][CH2:96][CH2:97][CH2:98][CH3:99])[O:70][P:69](=[O:106])([O:13][C:51]2[CH:52]=[CH:53][CH:54]=[CH:55][CH:56]=2)[O:68]1)[CH2:62][CH2:63][CH3:64]

Participants

7

Reactant 5

HCID 1049PyridineHCID 218852-DimethylaminopyridineHCID 69990Phenylphosphonic dichlorideHCID 53993884HCID 53993884, compoundHCID 86752773HCID 86752773, compound

Product 1

HCID 67556213HCID 67556213, compoundYield 21%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

It is prepared from 4-dodecyloxy-N,N-di(2-hydroxy-3-butoxy)-propyl aniline (5.38 g, 10 mmol), pyridine (3 g, 30 mmol), dimethylaminopyridine (0.2 g) and phenylphosphonic dichloride (2.32 g, 11 mmol) in dichloromethane as described for compound 200 to obtain a white solid 1.44 g (21%) and its isomer 1.4 g (20% a white solid).

Sources & evidence

ORD record
ord-425259ae1f374251b2e71cf2d1ceeefa
Source dataset
uspto-grants-1999_09
Patent number
US05958663

Reaction notes

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