Hydrochloric Acid → HCID 21190249, compound

HRID 619426Notes

Reaction equation

HRID 619426 reaction equation
[CH2:1]([C:3]1[N:4]=[C:5]2[N:14]3[C:9]([CH2:10][N:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:20][S:21]([C:24]([F:27])([F:26])[F:25])(=[O:23])=[O:22])[CH2:12][C:13]=13)=[CH:8][CH:7]=[CH:6]2)[CH3:2].[ClH:28]>C(O)C>[ClH:28].[ClH:28].[CH2:1]([C:3]1[N:4]=[C:5]2[N:14]3[C:9]([CH2:10][N:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:20][S:21]([C:24]([F:26])([F:25])[F:27])(=[O:22])=[O:23])[CH2:12][C:13]=13)=[CH:8][CH:7]=[CH:6]2)[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190149HCID 21190149, compound

Product 1

HCID 21190249HCID 21190249, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture of 10 ml of ethanol and 1 ml of 12N HCl was dissolved 542 mg (1.34 mmol) of 4,5-dihydro-2-ethyl-4-(5-trifluoromethanesulfonamidopentan-1-yl)-3H-1,4,8b-triazaacenaphthylene. The solvent was distilled off under reduced pressure to leave 640 mg of the desired compound (100%, white amorphous substance).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-104c87b9ab6741a09bfae2346a62ac07
Source dataset
uspto-grants-1999_09
Patent number
US05958942

Reaction notes

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