反应详情

To a solution of 702 mg (1.68 mmol) of 1,2-dihydro- 3-methyl-1-[6-[(2,2,2-trifluoro)ethanesulfonamido]hexan-1-yl]-1,4,7b-triazacyclopent[cd]inden-2-one in 15 ml of methanol was added 0.17 ml of conc. HCl, then the solvent was distilled off. To the residue were added acetone and ether. The resulting crystals were washed with ether and dried to give 718 mg of the desired compound (94.1%, colorless crystals), m.p.141.0-143.0° C.

1. distillationthe solvent was distilled off
2. additionTo the residue were added acetone and ether
3. washThe resulting crystals were washed with ether
4. customdried