Hydrochloric Acid → HCID 21190284, compound

HRID 619463Notes

Reaction equation

HRID 619463 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][N:13]2[C:23](=[O:24])[C:22]3[N:25]4[C:15](=[CH:16][N:17]=[C:18]4[CH:19]=[CH:20][CH:21]=3)[C:14]2=[O:26])=[CH:8][CH:7]=1)(=[O:4])=[O:3].[ClH:27]>CO>[ClH:27].[CH3:1][S:2]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][N:13]2[C:23](=[O:24])[C:22]3[N:25]4[C:15](=[CH:16][N:17]=[C:18]4[CH:19]=[CH:20][CH:21]=3)[C:14]2=[O:26])=[CH:8][CH:7]=1)(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190176HCID 21190176, compound

Product 1

HCID 21190284HCID 21190284, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 248 mg (0.67 mmol) of 4,5-dihydro-4-[4-(methanesulfonamido)phenylmethyl]-3H-1,4,8b-triazaacenaphthylene-3,5-dione in 15 ml of methanol was added 0.09 ml of conc. HCl. The solvent was distilled off. To the residue was added acetone. The resulting solid was washed with acetone and dried to afford 273 mg of the desired compound (100%, a colorless solid).

Workup

  1. distillationThe solvent was distilled off
  2. additionTo the residue was added acetone
  3. washThe resulting solid was washed with acetone
  4. customdried

Sources & evidence

ORD record
ord-bf7e2c4250e44085a8d8307c2b515415
Source dataset
uspto-grants-1999_09
Patent number
US05958942

Reaction notes

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