Hydrochloric Acid → HCID 21190124, compound

HRID 619481Notes

Reaction equation

HRID 619481 reaction equation
[F:1][C:2]([F:30])([F:29])[S:3]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][N:15]2[C:25](=[O:26])[C:24]3[N:27]4[C:17](=[CH:18][N:19]=[C:20]4[CH:21]=[CH:22][CH:23]=3)[C:16]2=[O:28])=[CH:9][CH:8]=1)(=[O:5])=[O:4].[ClH:31]>CO>[ClH:31].[F:29][C:2]([F:1])([F:30])[S:3]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][N:15]2[C:25](=[O:26])[C:24]3[N:27]4[C:17](=[CH:18][N:19]=[C:20]4[CH:21]=[CH:22][CH:23]=3)[C:16]2=[O:28])=[CH:9][CH:8]=1)(=[O:4])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190125HCID 21190125, compound

Product 1

HCID 21190124HCID 21190124, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 59 mg (0.13 mmol) of 4,5-dihydro-4-[2-[4-(trifluoromethanesulfonamido)phenyl]ethan-1-yl]-3H-1,4,8b-triazaacenaphthylene-3,5-dione in 5 ml of methanol was added 0.05 ml of conc. hydrochloric acid. The solvent was distilled off to afford 64 mg of the desired compound (100%, a pale yellow solid).

Workup

  1. distillationThe solvent was distilled off

Sources & evidence

ORD record
ord-abd85ab9d36a4e8cb96e16f728567bdc
Source dataset
uspto-grants-1999_09
Patent number
US05958942

Reaction notes

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