HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Diaminopyridine → HCID 21190091, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Diaminopyridine | HCID 8861 | — |
| Reactant | Ethyl 2-chloroacetoacetate | HCID 11858 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21190091 | HCID 21190091 | 57.1% |
Reaction Steps
To a suspension of 43.7 g (0.40 mol) of 2,6-diaminopyridine in 400 ml of ethanol was added 131.7 g (0.8 mol) of ethyl 2-chloroacetoacetate. The mixture was heated for 18 hours under reflux. After cooling, the resulting crystals was collected by filtration, washed with ethanol and ether successively to give 58.4 g of the desired compound (57.1%, pale yellow crystals).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958942 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-844a200ffc2b4f43b86336398edc5046 |
| Source note | uspto-grants-1999_09 |