Pyridine → HCID 136340738, compound

HRID 619547Notes

Reaction equation

HRID 619547 reaction equation
[C:1]1([C:7]2[N:12]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:10]=[C:9]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH:26]4[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]4[OH:32])=[CH:21][C:20]=3[OH:33])[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:34](Cl)(=[O:36])[CH3:35].N1C=CC=CC=1>C1(C)C=CC=CC=1>[C:13]1([C:11]2[N:12]=[C:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[N:8]=[C:9]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH:26]4[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]4[O:32][C:34](=[O:36])[CH3:35])=[CH:21][C:20]=3[OH:33])[N:10]=2)[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 136138660HCID 136138660, compound

Product 1

HCID 136340738HCID 136340738, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 13.0 g (29.6 mmol) of 2,4-diphenyl-6-(2'-hydroxy4'-(2"-hydroxycyclohexyloxy)phenyl)-1,3,5-triazine, 7.0 g (89.2 mmol) of acetyl chloride (Fluka, 99%) and 0.6 g (7.6 mmol) of pyridine in 140 ml of toluene (Merck, 99.5%) is stirred under nitrogen and held at 50° C. for 6 h.

Sources & evidence

ORD record
ord-3db426fa9cdf44c697aae59cc00794c4
Source dataset
uspto-grants-1999_09
Patent number
US05959008

Reaction notes

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