反应详情

A solution of 2.8 g of 2,6-dimethyl-3-nitrobenzaldehyde in 150 ml of toluene was treated with 5 ml of ethylene glycol and 20 mg of p-toluenesulphonic acid. The mixture was heated to reflux for 18 hours, with the water being separated using a separator. The mixture was left to cool to room temperature and was washed twice with water. After drying over anhydrous magnesium sulphate the solvent was evaporated and the crystalline residue was crystallized from hexane. 3.0 g of 2-(2,6-dimethyl-3-nitrophenyl)-1,3-dioxolane, m.p. 69-71° C., were obtained.

1. temperatureThe mixture was heated
2. customseparated
3. waitThe mixture was left
4. washwas washed twice with water
5. dry with materialAfter drying over anhydrous magnesium sulphate the solvent
6. customwas evaporated
7. customthe crystalline residue was crystallized from hexane