HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 21846931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-2-fluoro-1-nitrobenzene | HCID 69691 | — |
| Reactant | 5-Isoquinolinethiol | HCID 11051963 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21846931 | HCID 21846931 | 92.7% |
Reaction Steps
According to the method in Example 10, a mixture of 5-isoquinolinethiol 500 mg (3.1 mmol), DMF 10 ml, potassium carbonate 700 mg (5.1 mmol) and 4-chloro-2-fluoronitrobenzene 800 mg (5.0 mmol) was stirred at room temperature for 2 hours, and 5-(5-chloro-2-nitrophenylsulfanyl)isoquinoline 910 mg (92.7%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05959107 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-1235be1f045a4acebd0213536da12b36 |
| Source note | uspto-grants-1999_09 |