HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 21846928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-Chloro-3-nitropyridin-2-ylamine | HCID 2724035 | — |
| Reactant | 5-Isoquinolinethiol | HCID 11051963 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21846928 | HCID 21846928 | 86.7% |
Reaction Steps
According to the method in Example 10, a mixture of 5-isoquinolinethiol 300 mg (1.9 mmol), DMF 10 ml, potassium carbonate 520 mg (3.7 mmol) and 2-amino-6-chloro-3-nitropyridine 300 mg (1.9 mmol) was stirred at room temperature for 30 minutes, and 6-(5-isoquinolylsulfanyl)-3-nitro-2-pyridylamine 460 mg (86.7%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05959107 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-82216d9211f544509ded7c5866f0614c |
| Source note | uspto-grants-1999_09 |