HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 135822815, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Isoquinolinethiol | HCID 11051963 | — |
| Reactant | HCID 135822814 | HCID 135822814 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 135822815 | HCID 135822815 | 89.2% |
Reaction Steps
According to the method in Example 10, a mixture of 5-isoquinolinethiol 150 mg (0.9 mmol), DMF 5 ml, potassium carbonate 250 mg (1.8 mmol) and 7-chloro-2-methyl-6-nitro-3,4-dihydro-4-quinazolinone 200 mg (0.8 mmol) was stirred at room temperature for 2 hours, and 7-(5-isoquinolylsulfanyl)-2-methyl-6-nitro-3,4-dihydro-4-quinazolinone 260 mg (83.7%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05959107 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-7654c496dde544688d7ee244722ba46b |
| Source note | uspto-grants-1999_09 |