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HRID619793

反应详情

EQUATION

反应方程式

HRID 619793 的结构方程式

REACTANTS

反应物

2
结构：COc1ccccc1-c1ccc(S(=O)(=O)Cl)cc1
HCID10636676

未命名化合物

结构：Cl.N#Cc1cccc(CN2CC[C@H](N)C2=O)c1
HCID22870786

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccccc1-c1ccc(S(=O)(=O)N[C@H]2CCN(Cc3cccc(C#N)c3)C2=O)cc1
HCID10813876

N-[(3S)-1-[(3-Cyanophenyl)methyl]-2-oxo-3-pyrrolidinyl]-2′-methoxy[1,1′-biphenyl]-4-sulfonamide

C25H23N3O4S

PROCEDURE

实验过程

The title compound is prepared from 3-(3-(S)-amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride as in EXAMPLE 24, Part B using 2'-methoxybiphenyl-4-sulfonyl chloride in place of 6-methoxynaphthalene-2-sulfonyl chloride. The crude product is purified by column chromatography eluting with a gradient of 10% EtOAc/CH2Cl2 to 20% EtOAc/CH2Cl2 to give the title compound as a white foam.

WORKUP

后处理

  1. customThe crude product is purified by column chromatography
  2. washeluting with a gradient of 10% EtOAc/CH2Cl2 to 20% EtOAc/CH2Cl2