HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-methylimidazol-2-yl)benzenesulfonyl Chloride → HCID 10646532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-methylimidazol-2-yl)benzenesulfonyl Chloride | HCID 10801111 | — |
| Reactant | 3-(3-(S)-Amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride | HCID 22870786 | — |
| Product | HCID 10646532 | HCID 10646532 | — |
Reaction Steps
The title compound is prepared from 3-(3-(S)-amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride as in EXAMPLE 24, Part B using (1-methyl-1H-imidazol-2-yl)benzene-4-sulfonyl chloride in place of 6-methoxynaphthalene-2-sulfonyl chloride. The crude product is purified by column chromatography eluting with 5% MeOH/CH2Cl2 to give the title compound as a white foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958918 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-1c4a2df589df465b9da03f6d10bf446b |
| Source note | uspto-grants-1999_09 |