HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10682327, compound → HCID 10526725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10682327 | HCID 10682327 | — |
| Reactant | 3-(3-(S)-Amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride | HCID 22870786 | — |
| Product | HCID 10526725 | HCID 10526725 | — |
Reaction Steps
The title compound is prepared from 3-(3-(S)-amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride (0.3 g, 1.2 mmol) as in EXAMPLE 24, Part B using 4-pyridin-3-ylbenzenesulfonyl chloride (0.57 g, 2.4 mmol) in place of 6-methoxynaphthalene-2-sulfonyl chloride. The crude product is purified by chromatography (2.5% MeOH/CH2Cl2 to 5% MeOH/CH2Cl2) to obtain a white solid (0.08 g, 0.18 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958918 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-33a5a74736ef406f90e7dc3d66746eb3 |
| Source note | uspto-grants-1999_09 |