反应详情

温度

200 °C

4-Methyl-1-methoxynaphthalene (4) (145 g) was mixed with pyridine hydrochloride (250 g) and the mixture was heated at 200° C. for 3 hours. The mixture was cooled, treated with dilute hydrochloric acid, and extracted with ether. The ether extract was dried (MgSO4), filtered and the solvent removed, leaving a black oil which was extracted with petroleum b.p. 60°-80° C. (4×100 cm3). 4-Methyl-1-naphthol (5) was obtained as near colourless oily crystals which darken on storage.

1. temperatureThe mixture was cooled
2. extractionextracted with ether
3. extractionThe ether extract
4. dry with materialwas dried (MgSO4)
5. filtrationfiltered
6. customthe solvent removed
7. customleaving a black oil which
8. extractionwas extracted with petroleum b.p. 60°-80° C. (4×100 cm3)