Methyl iodide → HCID 21247478, compound

HRID 619980Notes

Reaction equation

[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([CH3:8])[CH2:4][CH2:3]1.IC.[CH2:11](Cl)[Cl:12]>>[Cl-:12].[CH3:8][N+:5]1([CH3:11])[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]1

Participants

Reactant 3

HCID 6328Methyl iodide

HCID 6344Dichloromethane

HCID 660484-Piperidinol, 1-methyl-

Product 1

HCID 21247478HCID 21247478, compound

Procedure

This compound was prepared by the procedure described for 2-[4-(N,N,N-trimethylammonium)phenyl]ethanol chloride. Typical reagent levels were as follows: 4-hydroxy-1-methylpiperidine (21.7 g, 0.188 mol), iodomethane (40.0 g, 0.280 mol), and methylene chloride (50 ml).

Workup

customThis compound was prepared by the procedure

Sources & evidence

ORD record: ord-ec583dbf625c4dfb97f56f41d72eb027
Source dataset: uspto-grants-1989_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04818426

Reaction notes

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