Acetone → HCID 14456454, compound

Participants

Reaction Steps

1-isoamyl-2-chloromethylbenzimidazole (2.9 g, 12.2 mmol) prepared in the preceding step (b), 4-aminopyridine (3.9 g, 22.5 mmol) and ethanol (24 ml) were refluxed. After concentration of the reaction mixture in vacuo, the product was crystallized from acetone (2.9 g, 9.0 mmol) and recrystallized from ethanol, than the objective compound (1.5 g, 4.5 mmol) was obtained.

Provenance & Evidence