2-(Dimethylamino)-1-phenylethanol → N,N-Dimethylphenylethylamine

HRID 620072Notes

Reaction equation

HRID 620072 reaction equation
[CH3:1][N:2]([CH3:12])[CH2:3][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)O>ClCCl>[CH3:12][N:2]([CH3:1])[CH2:3][CH2:4][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

3

Reactant 1

HCID 1208462-(Dimethylamino)-1-phenylethanol

Product 1

HCID 25125N,N-Dimethylphenylethylamine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

As Example 15 but using 2-dimethylamino-1-phenyl-ethanol (13.7 g) instead of 3-acetylpyridine. The crude material is pyrified by column chromatography on aluminium oxide using dichloromethane as eluant. The product is dried in vacuo to constant weight to give 1-(1,3-dithian-2-ylidene)-2-ylidene)-2-dimethylamino-1-phenylethane as an oil at room temperature.

Workup

  1. customThe product is dried in vacuo to constant weight

Sources & evidence

ORD record
ord-e0339d7105714941bca1842eb68379c8
Source dataset
uspto-grants-1989_04
Patent number
US04818765

Reaction notes

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